Baker J, Baker A J, Mazer C D
Department of Anaesthesia, St Michael's Hospital, Toronto, Ontario, Canada.
J Cardiothorac Vasc Anesth. 1995 Apr;9(2):154-7. doi: 10.1016/s1053-0770(05)80186-7.
Inadvertent postoperative hypothermia in the cardiac surgical patient can have various adverse physiologic effects. Previous studies have investigated the relationship of patient, surgical, and anesthetic factors with postoperative hypothermia in patients undergoing noncardiac surgery. This study was designed to assess the relationship between postoperative hypothermia after normothermic cardiopulmonary bypass (CPB) for cardiac surgery and a variety of perioperative and patient factors. Fifty-six patients undergoing daytime elective or urgent cardiac surgery with warm (37 degrees C) CPB were studied. The following patient variables were included: age, weight, height, sex, history of previous cardiac surgery, and prebypass temperature. The following treatment factors were recorded: type of surgery, type and dose of anesthetic, use of airway humidifier, use of an intravenous (i.v.) fluid warmer, total volume of i.v. fluid administered during surgery, net fluid volume administered via CPB, total time spent on CPB, use of nitroglycerin, use of alpha-agonists during surgery, and elapsed time from end of CPB to end of surgery. Core temperature readings, as measured by a pulmonary artery catheter thermistor, were noted as follows: (1) on insertion of the pulmonary artery catheter; (2) after the patient was weaned from CPB; (3) within 30 minutes of intensive care unit (ICU) arrival; (4) 3 to 5 hours after ICU arrival; (5) 7 to 9 hours after ICU arrival; and (6) 11 to 13 hours after ICU arrival. Multiple linear regression and logistic regression for categorical variables with backward elimination were employed to determine the impact of all variables on lowest postoperative temperature. The lowest mean temperature occurred during CPB.(ABSTRACT TRUNCATED AT 250 WORDS)
心脏手术患者术后意外体温过低会产生多种不良生理影响。先前的研究调查了非心脏手术患者的患者、手术及麻醉因素与术后体温过低的关系。本研究旨在评估心脏手术在常温体外循环(CPB)后出现的术后体温过低与各种围手术期因素及患者因素之间的关系。对56例接受日间择期或急诊心脏手术且采用体温37摄氏度的CPB的患者进行了研究。纳入了以下患者变量:年龄、体重、身高、性别、既往心脏手术史及体外循环前体温。记录了以下治疗因素:手术类型、麻醉类型及剂量、气道加湿器的使用、静脉(i.v.)液体加温器的使用、手术期间静脉液体的总输注量、通过CPB输注的净液体量、CPB的总时长、硝酸甘油的使用、手术期间α-激动剂的使用以及从CPB结束至手术结束的 elapsed 时间。通过肺动脉导管热敏电阻测量的核心体温读数记录如下:(1)肺动脉导管插入时;(2)患者脱离CPB后;(3)进入重症监护病房(ICU)后30分钟内;(4)进入ICU后3至5小时;(5)进入ICU后7至9小时;(6)进入ICU后11至13小时。采用多元线性回归及对分类变量进行向后排除的逻辑回归来确定所有变量对术后最低体温的影响。最低平均体温出现在CPB期间。(摘要截断于250字)