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[眼球摘除术后综合征的预防:羟基磷灰石硅橡胶植入物。初步实验研究及初步临床经验]

[Prevention of postenucleation syndrome: the hydroxylapatite silicone implant. Preliminary experimental studies and initial clinical experiences].

作者信息

Guthoff R, Vick H P, Schaudig U

机构信息

Universitäts-Augenklinik Rostock.

出版信息

Ophthalmologe. 1995 Apr;92(2):198-205.

PMID:7780281
Abstract

An orbital implant after enucleation compensates for volume deficiency and increases prosthesis motility. In the literature, however, an extrusion rate of orbital implant between 10 and 25% is reported. Since the introduction of hydroxylapatic ceramics (HAC), these numbers have been reduced considerably. The HAC, which is derived from corals, has a rough surface and requires a scleral covering for implantation. The HAC, which is made in the laboratory, can be produced with smoother surfaces, so that a homoplastic covering is no longer mandatory. A composite implant was developed to improve prosthesis motility further. This consists of artificial HAC at its anterior surface to guarantee safe tissue integration; the posterior part of the implant is manufactured from silicon rubber to create a jointlike structure in Tenon's capsule. Integration of the porous HAC in the orbital soft tissues has been tested and confirmed by animal experiments. After 30 full HAC implants and 25 composite implants, only one extrusion occurred. In all other cases, compatibility proved to be excellent; transmission of the motility to the prosthesis was moderate to good. Examinations comparing prosthesis motility and computer tomographically evaluated implant motility enabled the analysis of deficits in motility transmission of the implant for the artificial eye.

摘要

眼球摘除术后植入眼眶植入物可弥补体积不足并增加义眼的活动度。然而,文献报道眼眶植入物的挤出率在10%至25%之间。自羟基磷灰石陶瓷(HAC)问世以来,这些数字已大幅降低。源自珊瑚的HAC表面粗糙,植入时需要巩膜覆盖。实验室制造的HAC表面可以更光滑,因此不再强制要求同种异体覆盖。为进一步改善义眼活动度,研发了一种复合植入物。它的前表面由人工HAC组成,以确保安全的组织整合;植入物的后部由硅橡胶制成,在Tenon囊内形成类似关节的结构。多孔HAC在眼眶软组织中的整合已通过动物实验进行了测试和证实。在植入30个完整的HAC植入物和25个复合植入物后,仅发生了一次挤出。在所有其他情况下,兼容性都非常好;活动度传递到义眼的效果为中等至良好。通过比较义眼活动度和计算机断层扫描评估的植入物活动度进行的检查,能够分析植入物向假眼传递活动度时的缺陷。

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