Norris M K, Fuhrman B P, Leach C L
AACN Clin Issues Crit Care Nurs. 1994 Aug;5(3):246-54. doi: 10.4037/15597768-1994-3004.
Liquid ventilation is, by all initial considerations, an unconventional concept. Decades of research, however, have found that by using perfluorocarbons, which are capable of holding high concentrations of critical gases such as oxygen and carbon dioxide, gas exchange optimal enough to support life is possible with no known toxic effects. The earliest method of liquid ventilation, tidal liquid breathing, involved infusion and active removal of tidal volumes of perfluorocarbons by a liquid ventilator for gas exchange. Recently, a new method of partial liquid breathing, called perfluorocarbon-associated gas exchange, makes the process of liquid ventilation simpler by using conventional gas ventilators. Current research is showing great promise in the use of liquid ventilation for patients with pulmonary pathology. Critical care nurses should become knowledgeable of this new mode of ventilation and be prepared to meet the special needs of this unique population.
从所有初步考虑来看，液体通气是一个非传统的概念。然而，数十年的研究发现，通过使用全氟化碳（其能够容纳高浓度的关键气体，如氧气和二氧化碳），可以实现足以支持生命的最佳气体交换，且无已知的毒性作用。最早的液体通气方法，即潮式液体呼吸，涉及通过液体通气机输注和主动排出潮气量的全氟化碳以进行气体交换。最近，一种名为全氟化碳相关气体交换的部分液体呼吸新方法，通过使用传统气体通气机使液体通气过程更简单。目前的研究表明，液体通气在肺部疾病患者中的应用前景广阔。重症护理护士应了解这种新的通气模式，并准备好满足这一独特人群的特殊需求。
