Zakharov I S, Paputskaia N I, Pozharov A V, Lepiakhov A Iu
Med Tekh. 1995 Jan-Feb(1):32-6.
The paper provides evidence for perspectives of the toxicological equipment for protozoa chemotaxis bioassay, which allows one to solve the problems in preparing a culture, a sample, testing solutions and measurement of protozoan reactions. A Poisson process device was proposed to use for construction of a mathematical model of a protozoan concentration transducer. The experimental findings supported the dependence theoretically forwarded. With the new approach, a BIOTESTER-2 device was designed, which has found its use in controlling the quality of water, antibiotics, in mapping the contamination of areas. The device may be used in the evaluation of the toxicity of biological fluids.
本文为原生动物趋化性生物测定的毒理学设备的相关观点提供了证据，该设备能够解决培养物、样品、测试溶液的制备以及原生动物反应测量等问题。提出了一种泊松过程装置用于构建原生动物浓度传感器的数学模型。实验结果支持了理论上提出的相关性。采用新方法设计了BIOTESTER - 2设备，该设备已用于水、抗生素质量控制，区域污染测绘。该设备可用于评估生物流体的毒性。
