Kelly K M
Department of Neurology, University of Michigan Medical Center, Ann Arbor, USA.
Neurology. 1995 Jun;45(6):1211-3. doi: 10.1212/wnl.45.6.1211.
I report a 35-year-old woman with occult coronary artery disease who experienced cardiac arrest within minutes after receiving a first-time dose of subcutaneous sumatriptan for migraine. The patient was resuscitated, and subsequent serial cardiac enzymes indicated myocardial infarction. Because sumatriptan can cause coronary artery vasospasm, patients with significant risk factors for coronary artery disease should be carefully evaluated for cardiovascular disease prior to the use of sumatriptan.
我报告了一名35岁患有隐匿性冠状动脉疾病的女性，她在首次皮下注射舒马曲坦治疗偏头痛后几分钟内发生心脏骤停。患者经复苏成功，随后连续的心肌酶检查提示心肌梗死。由于舒马曲坦可引起冠状动脉血管痉挛，对于有冠状动脉疾病显著危险因素的患者，在使用舒马曲坦之前应仔细评估其心血管疾病情况。
