Meda N, Soula G, Dabis F, Cousens S, Some A, Mertens T, Salamon R
Service de gynécologie-obstétrique, Centre Hospitalier National Sourô Sanou, Burkina Faso.
Rev Epidemiol Sante Publique. 1995;43(3):215-24.
A case-control study to investigate determinants of preterm delivery and intrauterine growth retardation (IUGR) in Bobo-Dioulasso, Burkina Faso, was conducted between December 1991 and November 1992. A total of 581 cases were recruited, 281 preterm infants with birthweight < 2500 g and 300 term infants with birthweight < 2500 g. 578 infants born at term with birthweights of 2500 g or more were recruited as controls. Logistic regression analyses identified three factors linked independently to both preterm delivery and IUGR: maternal illness during the pregnancy, nulliparity and failure to attend three antenatal consultations. In addition, primiparity and a maternal weight < 50 kg were associated with an increased risk of preterm delivery. Other factors associated with increased risk of IUGR were maternal height less than or equal to 155 cm, mid-upper arm circumference < 24 cm, and female sex of the infant. Improvements in the pre-pregnancy weight of women and in antenatal care focused on nulli- and primiparous women might in this population, reduce substantially the incidence of preterm delivery and IUGR.
1991年12月至1992年11月，在布基纳法索博博迪乌拉索开展了一项病例对照研究，以调查早产和宫内生长受限（IUGR）的决定因素。共招募了581例婴儿，其中281例为出生体重<2500g的早产儿，300例为出生体重<2500g的足月儿。招募了578例出生体重2500g及以上的足月儿作为对照。逻辑回归分析确定了与早产和宫内生长受限均独立相关的三个因素：孕期母亲患病、初产以及未参加三次产前检查。此外，初产和母亲体重<50kg与早产风险增加相关。与宫内生长受限风险增加相关的其他因素包括母亲身高小于或等于155cm、上臂中部周长<24cm以及婴儿为女性。改善该人群中女性的孕前体重，并针对初产妇和经产妇加强产前保健，可能会大幅降低早产和宫内生长受限的发生率。
