Vico L, Pouget J F, Calmels P, Chatard J C, Rehailia M, Minaire P, Geyssant A, Alexandre C
GIP Exercice Faculté de Médecine, Saint-Etienne, France.
J Bone Miner Res. 1995 Mar;10(3):374-83. doi: 10.1002/jbmr.5650100307.
In this cross-sectional study of 55 women (mean age 73.54 +/- 5.87), the magnitude of the relation between different indices of physical ability and confounding factors to bone density were determined. Physical fitness was assessed by direct measurement of maximal oxygen consumption (VO2 max), isokinetic muscle strength, and quadriceps and psoas muscle surfaces and densities using computed tomography. Anthropometry, chronological and gynecological ages, and dietary calcium intake were also recorded. The bone mineral density (BMD) was evaluated at the axial level (lumbar spine and proximal femur) and at the peripheral level (radius and tibia, cancellous and cortical compartments). Parameters related to physical ability proved to be the best predictors of BMD in radial and tibial cancellous compartments, spine, femoral neck, and trochanter, accounting for 15-27.5% of the total variance. The VO2 max was a major determinant of the femoral mineral density and one of the predictors of radial and tibial cancellous compartments. Psoas parameters were strongly related to spine mineral density and also constituted a predictor of radius (cancellous) and tibia mineral densities. The arm muscle strength could predict, though weakly, the BMD of axial skeleton, whereas thigh muscle strength only predicted the BMD of inferior limbs. No correlation was observed between current dietary calcium intake and BMD. Age-postmenopause and fertile life remained predictive of BMD at mostly cancellous sites, whereas anthropometry exerted important effects on radial and tibial cortices. The study suggests distinct sets of relations between physical ability and the BMD variables. Subjects with greater and denser psoas muscles had greater spine BMD, and those with higher VO2 max had greater proximal femur BMD.
在这项针对55名女性（平均年龄73.54±5.87岁）的横断面研究中，确定了身体能力的不同指标与骨密度混杂因素之间关系的大小。通过直接测量最大耗氧量（VO2 max）、等速肌力以及使用计算机断层扫描测量股四头肌和腰大肌的表面积和密度来评估身体素质。还记录了人体测量学数据、实际年龄和妇科年龄以及膳食钙摄入量。在轴向水平（腰椎和股骨近端）和外周水平（桡骨和胫骨，松质骨和皮质骨部分）评估骨矿物质密度（BMD）。事实证明，与身体能力相关的参数是桡骨和胫骨松质骨部分、脊柱、股骨颈和大转子处骨密度的最佳预测指标，占总方差的15 - 27.5%。VO2 max是股骨矿物质密度的主要决定因素之一，也是桡骨和胫骨松质骨部分的预测指标之一。腰大肌参数与脊柱矿物质密度密切相关，也是桡骨（松质骨）和胫骨矿物质密度的预测指标之一。手臂肌肉力量虽然对轴向骨骼的骨密度预测作用较弱，但可以预测，而大腿肌肉力量仅能预测下肢的骨密度。目前的膳食钙摄入量与骨密度之间未观察到相关性。绝经后年龄和生育期在大多数松质骨部位仍然是骨密度的预测因素，而人体测量学对桡骨和胫骨皮质骨有重要影响。该研究表明身体能力与骨密度变量之间存在不同的关系集。腰大肌更大且更致密的受试者脊柱骨密度更高，而VO2 max更高的受试者股骨近端骨密度更高。
