Kuniyoshi N, Sagara H, Nagataki S, Hirosawa K
Department of Ophthalmology, University of Ryukyu, Faculty of Medicine, Okinawa-ken, Japan.
Nippon Ganka Gakkai Zasshi. 1995 May;99(5):526-31.
The morphology and permeability to horseradish peroxidase (HRP) of the ciliary muscle capillaries of squirrel monkeys were studied. The endothelial cells of the capillaries were of the continuous type and the interendothelial clefts were closed by a zonula occludens. Many vesicles were present in the cytoplasm of the endothelial cells. In addition to these vesicles, large vacuole-like structures, 100-500 nm in diameter, were observed in the cytoplasm of capillary endothelium, especially in the circular and radial ciliary muscles. When HRP was perfused into the anterior chamber, the 3,3'-diaminobenzidine reaction product was observed in the lumen of the ciliary muscle vessels after 30 minutes. When HRP was administered intravenously, the reaction product was observed among the muscle fiber bundles after 15 minutes. In both cases, the reaction products were also present in the cytoplasmic vesicles and vacuole-like structures, suggesting that these structures are involved in the bidirectional transport of HRP between interstitium and blood.
对松鼠猴睫状肌毛细血管的形态及对辣根过氧化物酶（HRP）的通透性进行了研究。毛细血管的内皮细胞为连续型，内皮细胞间裂被紧密连接封闭。内皮细胞的细胞质中有许多小泡。除这些小泡外，在毛细血管内皮细胞质中还观察到直径为100 - 500纳米的大泡状结构，尤其在环形和放射状睫状肌中。当将HRP灌注到前房时，30分钟后在睫状肌血管腔内观察到3,3'-二氨基联苯胺反应产物。当静脉注射HRP时，15分钟后在肌纤维束之间观察到反应产物。在这两种情况下，反应产物也存在于细胞质小泡和泡状结构中，表明这些结构参与了HRP在间质和血液之间的双向运输。
