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心血管高风险患者群体腹主动脉手术后的发病率和死亡率。

Morbidity and mortality after abdominal aortic surgery in a population of patients with high cardiovascular risk.

作者信息

Henderson A, Effeney D

机构信息

Princess Alexandra Hospital, Brisbane, Queensland, Australia.

出版信息

Aust N Z J Surg. 1995 Jun;65(6):417-20. doi: 10.1111/j.1445-2197.1995.tb01772.x.

Abstract

Postoperative myocardial infarction is a major risk factor in patients undergoing abdominal aortic surgery. Correction of cardiac ischaemia prior to abdominal aortic surgery improves outcome. The morbidity and mortality of 639 consecutive patients were reviewed from an area with poor access to cardiac surgery, operated upon in a single tertiary referral hospital for aortic aneurysm or aortobifemoral grafting. A total of 101 patients with ruptured aortic aneurysm who survived to reach the intensive care unit experienced a hospital mortality of 29%. Multiorgan failure was the cause of death in 48% and postoperative myocardial infarction in 31%. Of the 253 patients with intact aortic aneurysm, which included elective and urgent resection, the mortality was 9%. There was a high incidence of uncorrected pre-operative ischaemic heart disease and myocardial infarction was the major cause of death (62%). Pre-operative myocardial infarction was predictive of postoperative cardiac morbidity and mortality. Of the 285 patients undergoing aortobifemoral grafting the mortality was 3% despite a high incidence of pre-operative ischaemic heart disease. Further reductions in postoperative death from ruptured aortic aneurysm must await improved screening to diagnose and treat the aneurysm before rupture. In patients operated upon electively, improved pre-operative cardiac screening and coronary bypass grafting where appropriate, especially for patients with aortic aneurysm and previous myocardial infarction, may further reduce peri-operative mortality.

摘要

术后心肌梗死是接受腹主动脉手术患者的主要危险因素。腹主动脉手术前纠正心脏缺血可改善预后。我们回顾了来自一个心脏手术可及性较差地区的639例连续患者的发病率和死亡率,这些患者均在一家单一的三级转诊医院接受主动脉瘤或主动脉双股动脉移植手术。共有101例存活至重症监护病房的主动脉瘤破裂患者,其住院死亡率为29%。多器官功能衰竭是48%患者的死亡原因,术后心肌梗死是31%患者的死亡原因。在253例完整主动脉瘤患者中,包括择期和急诊切除术,死亡率为9%。术前未纠正的缺血性心脏病发病率很高,心肌梗死是主要死因(62%)。术前心肌梗死可预测术后心脏发病率和死亡率。在285例接受主动脉双股动脉移植手术的患者中,尽管术前缺血性心脏病发病率很高,但死亡率为3%。要进一步降低主动脉瘤破裂术后的死亡率,必须等待改进筛查方法,以便在动脉瘤破裂前进行诊断和治疗。对于择期手术的患者,改进术前心脏筛查并在适当情况下进行冠状动脉旁路移植术,特别是对于有主动脉瘤和既往心肌梗死的患者,可能会进一步降低围手术期死亡率。

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