Reinacher M, Wittmer G, Koberstein H, Failing K
Institut für Veterinär-Pathologie, Justus-Liebig-Universität Giessen.
Berl Munch Tierarztl Wochenschr. 1995 Feb;108(2):58-60.
Persistent FeLV infection was demonstrated in more than 3000 necropsied cats by an immunohistological method. The findings were associated with the diagnoses established by means of post-mortem examination, histopathological, bacteriological, virological, and parasitological investigations. Statistically significant differences between FeLV-positive and FeLV-negative cats in the relative risk for certain lesions could be demonstrated for the first time. As a consequence, the importance of FeLV infection for the development of certain lesions in cats is to be seen under new aspects for some diagnoses. The relative risk for development of anemia, e.g., is only slightly increased in FeLV-positive animals whereas the relative risk for focal myocardial necrosis and coccidiosis is elevated tremendously in these cats. The relative risk for some lesions and diagnoses is much higher in FeLV-negative cats than in FeLV-positive animals. This is true, e.g., for myocardiopathy and hemorrhagic cystitis.
通过免疫组织学方法在3000多只剖检猫中证实了持续性猫白血病病毒（FeLV）感染。这些发现与通过尸检、组织病理学、细菌学、病毒学和寄生虫学调查所确立的诊断相关。首次证明了FeLV阳性猫和FeLV阴性猫在某些病变相对风险上存在统计学显著差异。因此，对于某些诊断而言，FeLV感染对猫某些病变发展的重要性需要从新的角度来看待。例如，FeLV阳性动物发生贫血的相对风险仅略有增加，而这些猫发生局灶性心肌坏死和球虫病的相对风险则大幅升高。某些病变和诊断在FeLV阴性猫中的相对风险比FeLV阳性动物高得多。例如，心肌病和出血性膀胱炎就是如此。
