Verdrager J
Bull Soc Pathol Exot. 1995;88(1):54-9; discussion 59-60.
Cross-species transfer of simian immunodeficiency viruses (SIV) may occur accidentally. This transfer, with the possible exception of the virus of the sooty mangabey monkey, leads to a biological dead-end. Thus, only serial passages of the virus from man to man, through blood inoculation, could explain its progressive evolution from SIV to HIV. Such an artificial cycle may have been initiated, in the 1910s, following the introduction of syringes and needles into the region of the African Great Lakes, a region where some communities were considering that the inoculation of blood from certain individuals or from monkeys was a very powerful magical remedy. The first HIV-1 infection may have emerged in the 1940s, in one of these isolated communities among which the virus remained at first confined before spreading to other populations.
猿猴免疫缺陷病毒(SIV)的跨物种传播可能是偶然发生的。除了可能是乌黑白眉猴的病毒外,这种传播会导致生物学上的死胡同。因此,只有通过血液接种在人与人之间连续传代病毒,才能解释其从SIV到HIV的逐步进化。这样一个人为的循环可能在20世纪10年代随着注射器和针头传入非洲大湖地区而开始,在该地区的一些社区,人们认为接种某些个体或猴子的血液是一种非常有效的神奇疗法。首例HIV-1感染可能出现在20世纪40年代,在这些与世隔绝的社区之一中,病毒最初在其中受到限制,然后才传播到其他人群。