Bachy C, van Ypersele de Strihou C, Alexandre G P, Troch R
Proc Eur Dial Transplant Assoc. 1976;12:461-70.
The incidence of hypertension defined as a mean diastolic pressure above 90 mmHg has been evaluated in 85 transplanted patients with a follow-up ranging from 3 to 78 months. The proportion of hypertensive patients rises during the first three months and stabilises subsequently around 60 percent. Over the years hypertension fluctuates so that one-third of the initially hypertensive patients become normotensive, whereas one-third of the initially normotensive patients become hypertensive. The main single aetiological factor is renal failure. No clear relationship was found between prednisolone dosage and hypertension. Renal artery stenosis was found in 2.4 percent of the cases. Finally no single aetiological factor was found in one third of the hypertensive patients. It is speculated that in some of them, minute intrarenal vascular lesions are responsible for the hypertension and lead ultimately to decreased renal function.
对85例移植患者进行了评估,这些患者的平均舒张压高于90 mmHg即被定义为高血压,随访时间为3至78个月。高血压患者的比例在最初三个月内上升,随后稳定在60%左右。多年来,高血压情况波动不定,最初高血压患者中有三分之一血压恢复正常,而最初血压正常的患者中有三分之一变成高血压。主要的单一病因是肾衰竭。未发现泼尼松龙剂量与高血压之间存在明确关系。2.4%的病例发现有肾动脉狭窄。最后,三分之一的高血压患者未发现单一病因。据推测,其中一些患者的高血压是由微小的肾内血管病变引起的,最终导致肾功能下降。