Le Chalony C, Pibouin L, Hayes H, Apiou F, Dutrillaux B, Goubin G
URA 620 CNRS, Institut Curie, Section de Biologie, Paris, France.
Cytogenet Cell Genet. 1995;70(3-4):192-4. doi: 10.1159/000134031.
A clone carrying an open reading frame coding for a novel zinc finger protein of the Krüppel family was isolated from a bovine genomic library and designated ZNF 164 (zinc finger protein 164). Partial sequencing revealed that it contained at least 13 zinc finger motifs preceded by a lysine-rich region of 60 amino acids. The ZNF164 protein shared approximately 60% similarity with several zinc finger proteins but did not appear to be orthologous with a previously identified gene. Using fluorescence in situ hybridization, the ZNF164 gene was mapped to bovine chromosome band 17q24.
从牛基因组文库中分离出一个携带编码Krüppel家族新型锌指蛋白开放阅读框的克隆,并将其命名为ZNF 164(锌指蛋白164)。部分测序显示,它包含至少13个锌指基序,前面有一个由60个氨基酸组成的富含赖氨酸的区域。ZNF164蛋白与几种锌指蛋白具有约60%的相似性,但似乎与先前鉴定的基因不是直系同源的。使用荧光原位杂交技术,将ZNF164基因定位到牛染色体带17q24。