Mokrzyński S, Chlubek D, Machoy Z, Samujło D
Katedry i Zakładu Biochemii i Chemii Pomorskiej Akademii Medycznej w Szczecinie.
Ginekol Pol. 1994 Dec;65(12):678-81.
The authors present the results of measuring the content of fluoride, calcium and phosphates performed on material comprising 66 thigh bones of human fetus in 4 age groups. In the studies the division into epiphysis and metaphysis parts was taken into consideration. A prepared complication furnishes the ratios of calcium to fluoride and calcium to phosphates in epiphysis and metaphysis parts, as well as ratio of calcium in epiphysis to calcium in metaphysis parts of the studied bones in the respective age groups. It has been disclosed that the increasing fluoride cumulation in fetal bones is a signal that the human organism is likely to be exposed to fluorine action already during the fetal life period. The fluoride content in thigh bones of fetus does not correlate with the content of calcium and phosphates, which may be evidence that there is a lack of significant influence of the determined fluoride content on the mineralization process taking place in bones at this period of life.
作者展示了对4个年龄组的66块人类胎儿大腿骨材料进行氟、钙和磷酸盐含量测量的结果。在研究中，考虑了将其分为骨骺和干骺端部分。一个准备好的并发症提供了骨骺和干骺端部分钙与氟、钙与磷酸盐的比率，以及各年龄组所研究骨骼的骨骺中钙与干骺端中钙的比率。已经发现，胎儿骨骼中氟累积的增加表明人类机体在胎儿期就可能已经受到氟的作用。胎儿大腿骨中的氟含量与钙和磷酸盐的含量无关，这可能证明在此生命阶段所测定的氟含量对骨骼中发生的矿化过程缺乏显著影响。
