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氟洛芬对骨关节炎镇痛作用的安慰剂对照试验。

A controlled trial of the analgesic effects of Floctafenine against placebo in osteoarthrosis.

作者信息

Burke M J, Akabar F A, Wright V

出版信息

Rheumatol Rehabil. 1976 May;15(2):97-100. doi: 10.1093/rheumatology/15.2.97.

Abstract

Floctafenine 200 mg four times a day was compared with placebo in 30 out-patients with osteoarthrosis in a double-blind controlled study. There was a significant patient preference for, and a greater relief of pain with, floctafenine. Pain on walking and joint stiffness after sitting were significantly less on floctafenine. There were no differences in side-effects between floctafenine and placebo.

摘要

在一项双盲对照研究中,对30名骨关节炎门诊患者进行了比较,让他们每天服用4次200毫克的氟考芬那酯,并与服用安慰剂的情况进行对比。患者明显更倾向于选择氟考芬那酯,且该药物止痛效果更佳。服用氟考芬那酯后,行走时的疼痛以及久坐后的关节僵硬症状明显减轻。氟考芬那酯与安慰剂在副作用方面没有差异。

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