艾滋病患者的多克隆鸟分枝杆菌感染：从同一患者分离出的不同鸟分枝杆菌菌株的抗菌药敏性差异
Polyclonal Mycobacterium avium infections in patients with AIDS: variations in antimicrobial susceptibilities of different strains of M. avium isolated from the same patient.
作者信息
von Reyn C F, Jacobs N J, Arbeit R D, Maslow J N, Niemczyk S
机构信息
Infectious Disease Section, Dartmouth Medical School, Lebanon, New Hampshire, USA.
出版信息
J Clin Microbiol. 1995 Apr;33(4):1008-10. doi: 10.1128/jcm.33.4.1008-1010.1995.
Abstract
Broth microdilution MICs were determined for pairs of strains isolated from five AIDS patients with polyclonal Mycobacterium avium infection. Four (80%) of the five patients were infected simultaneously with strains having different antimicrobial susceptibility patterns. These findings have implications for the interpretation of susceptibility data in M. avium prophylaxis and treatment trials.
摘要
对从5例患有鸟分枝杆菌多克隆感染的艾滋病患者中分离出的菌株对进行肉汤微量稀释法测定最低抑菌浓度（MIC）。5例患者中有4例（80%）同时感染了具有不同抗菌药敏模式的菌株。这些发现对鸟分枝杆菌预防和治疗试验中药敏数据的解释具有重要意义。
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