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脑室内出血及其他医学和环境风险对三岁儿童多种结局的影响。

Effects of intraventricular hemorrhage and other medical and environmental risks on multiple outcomes at age three years.

作者信息

Bendersky M, Lewis M

机构信息

Institute for the Study of Child Development, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick 08903-0019, USA.

出版信息

J Dev Behav Pediatr. 1995 Apr;16(2):89-96.

PMID:7790520
Abstract

This study examined the interrelated effects of intraventricular hemorrhage (IVH), neonatal medical condition, and environmental quality on development. At age 3 years, the functioning of 105 preterms was assessed in a variety of cognitive areas. Analyses revealed that IVH was related to gross motor, receptive, and expressive communication ability. However, it was only the subjects who had severe IVH who performed significantly worse than the comparison subjects. Subjects who had hemorrhages confined to a germinal matrix or a small intraventricular bleed did not differ from the comparison subjects who performed at expected age levels. When medical condition, socioeconomic status, and family risk, a composite variable including proximal environmental measures, were examined together with IVH as predictors, IVH remained related to motor and receptive communication ability after controlling for the other variables. The number of other medical complications and the environmental factors had more wide-ranging effects. Each predictor was related to a unique set of outcomes.

摘要

本研究考察了脑室内出血(IVH)、新生儿健康状况和环境质量对发育的相关影响。在3岁时,对105名早产儿在多个认知领域的功能进行了评估。分析表明,IVH与粗大运动、接受性和表达性沟通能力有关。然而,只有患有严重IVH的受试者表现明显比对照受试者差。出血局限于生发基质或少量脑室内出血的受试者与在预期年龄水平表现的对照受试者没有差异。当将健康状况、社会经济地位和家庭风险(一个包括近端环境指标的复合变量)与IVH一起作为预测因素进行考察时,在控制其他变量后,IVH仍与运动和接受性沟通能力有关。其他医疗并发症的数量和环境因素具有更广泛的影响。每个预测因素都与一组独特的结果相关。

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