Saito R, Fujimura S, Shouji S, Ichinose T, Sayama T
Department of Thoracic Surgery, Tohoku University, Sendai, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1995 Apr;33(4):463-7.
A 59-year-old man had an abnormal shadow on chest X-ray film. He was admitted to Tohoku-chuou Hospital, and a lung lesion in the right lower lobe was diagnosed as a benign nodule. A new nodular lesion appeared on a chest X-ray film taken two months after his discharge from the hospital. Both lesions were in the same lobe; the older one was in segment 9 and the newer one was in segment 10. For the lesion in segment 10, malignancy was not ruled out, so open lung biopsy (right lower lobectomy) was done. With the findings of angitis and focal necrosis surrounded by granulomas consisting of epthelioid cells and multinuclear giant cells, the new lesion in segment 10 was diagnosed as necrotizing sarcoid granulomatosis. The older lesion in segment 9 was a tuberculoma. We conclude that in this case the open lung biopsy was necessary to diagnose necrotizing sarcoid granulomatosis in lung.
一名59岁男性胸部X光片出现异常阴影。他入住了东北中央医院,右下叶的肺部病变被诊断为良性结节。出院两个月后拍摄的胸部X光片上出现了一个新的结节性病变。两个病变都在同一肺叶;较老的病变在第9段,较新的病变在第10段。对于第10段的病变,不能排除恶性的可能,因此进行了开胸肺活检(右下叶切除术)。根据血管炎以及由上皮样细胞和多核巨细胞组成的肉芽肿所包围的局灶性坏死的检查结果,第10段的新病变被诊断为坏死性结节病样肉芽肿病。第9段较老的病变是结核瘤。我们得出结论,在这种情况下,开胸肺活检对于诊断肺部坏死性结节病样肉芽肿病是必要的。