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[坏死性结节病样肉芽肿病。附4例报告]

[Necrotizing sarcoid granulomatosis. Apropos of 4 cases].

作者信息

Sadoun D, Kambouchner M, Tazi A, Lattaignant J C, Margent P, Arondelle C, Carvaillo D, Groussard O, Battesti J P

机构信息

Service de Pneumologie, Hôpital Avicenne, Bobigny.

出版信息

Ann Med Interne (Paris). 1994;145(4):230-3.

PMID:8092646
Abstract

Necrotizing sarcoid granulomatosis (NSG) was first described by Liebow in 1973 among the heading "pulmonary angeitis and granulomatosis". We reported four cases of NSG. The diagnostic was made by open lung biopsy in all, and the distinctive features were those described by Liebow: presence of numerous sarcoid-like granulomas, foci of fibrinoid necrosis and granulomatous vasculitis. Clinical, radiological, and clinical course characteristics allow the reasonable conclusion that NSG is the histopathological substratum of a variety of sarcoidosis affections termed "nodular sarcoidosis".

摘要

坏死性结节病样肉芽肿病(NSG)于1973年由利博在“肺血管炎和肉芽肿病”标题下首次描述。我们报告了4例NSG。所有病例均通过开胸肺活检确诊,其特征与利博所描述的一致:存在大量结节病样肉芽肿、纤维素样坏死灶和肉芽肿性血管炎。临床、影像学及临床病程特征合理表明,NSG是多种被称为“结节性结节病”的结节病病变的组织病理学基础。

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