维生素E对全氯乙烯诱导细胞毒性中血清和组织糖蛋白水平的体内作用。
In vivo effect of vitamin E on serum and tissue glycoprotein levels in perchloroethylene induced cytotoxicity.
作者信息
Ebrahim A S, Gopalakrishnan R, Murugesan A, Sakthisekaran D
机构信息
Department of Medical Biochemistry, Post Graduate Institute of Basic Medical Sciences, University of Madras, India.
出版信息
Mol Cell Biochem. 1995 Mar 9;144(1):13-8. doi: 10.1007/BF00926735.
The antioxidant efficacy of vitamin E on Perchloroethylene (PER) induced cytotoxicity has been studied in rats. Feeding PER to rats for 42 days using sesame oil as vehicle alters total protein and protein bound carbohydrate components in liver and kidney of experimental animals. Supplementation of vitamin E prevented the changes observed in total protein and protein bound carbohydrate components of PER administered rats. Histopathological studies also show the effectiveness of vitamin E on PER administered rats in protecting the cellular architecture of liver and kidney from PER induced cytotoxicity.
已在大鼠中研究了维生素E对全氯乙烯（PER）诱导的细胞毒性的抗氧化功效。以芝麻油为载体给大鼠喂食PER 42天，会改变实验动物肝脏和肾脏中的总蛋白以及与蛋白结合的碳水化合物成分。补充维生素E可防止在给予PER的大鼠中观察到的总蛋白和与蛋白结合的碳水化合物成分的变化。组织病理学研究还表明，维生素E对给予PER的大鼠有效，可保护肝脏和肾脏的细胞结构免受PER诱导的细胞毒性影响。
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