de Groot P A
Psychiatrisch Ziekenhuis Veldwijk, Ermelo.
Ned Tijdschr Geneeskd. 1995 Jun 17;139(24):1237-41.
Depression is a frequent and treatable disorder, but it is insufficiently recognized. A generally used classification system is lacking. In a consensus meeting the following terms were defined: a normal feeling of depression, depression as a symptom and depression as an illness. The use of the term 'masked depression' was advised against. The undertreatment mentioned is caused by the following factors: presentation of physical symptoms by depressive patients, unfamiliarity of patients with depressive disorders and difficulties of patients and GPs in labelling depression as mental. Depressive disorders have various causes. For scoring the severity of depression the Bech version of the Hamilton Depression Rating Scale is preferred. There is no valid laboratory test for diagnosing depression. Laboratory tests are recommended to exclude physical disorders, for choosing an antidepressant and for the follow-up of drug treatment. Cognitive Behavioural Therapy and Interpersonal Therapy are preferred psychotherapeutic methods because of their scientifically proved efficacy. Women suffer from depression twice as frequently as men, which is due to social factors rather than to genetic or hormonal factors. Therefore hormonal therapy is not indicated, a more equal doctor-patient relationship is. Patients with a depressive disorder may consider suicide; this should regularly be discussed with them.
抑郁症是一种常见且可治疗的疾病,但它未得到充分认识。目前缺乏一个普遍使用的分类系统。在一次共识会议上,对以下术语进行了定义:正常的抑郁情绪、作为症状的抑郁和作为疾病的抑郁。会议建议不要使用“隐匿性抑郁症”这一术语。上述治疗不足是由以下因素导致的:抑郁症患者出现躯体症状、患者对抑郁症不熟悉以及患者和全科医生在将抑郁症归类为精神疾病方面存在困难。抑郁症有多种病因。对于评估抑郁症的严重程度,首选贝克版汉密尔顿抑郁量表。目前尚无用于诊断抑郁症的有效实验室检查。建议进行实验室检查以排除躯体疾病、选择抗抑郁药以及监测药物治疗效果。认知行为疗法和人际疗法是首选的心理治疗方法,因为它们的疗效已得到科学证明。女性患抑郁症的频率是男性的两倍,这是由社会因素而非遗传或激素因素导致的。因此,不建议进行激素治疗,而应建立更平等的医患关系。抑郁症患者可能会考虑自杀;应定期与他们讨论这一问题。