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[传染性单核细胞增多症中针对爱泼斯坦-巴尔病毒抗体的血清学研究]

[Serological studies of antibodies to Epstein-Barr virus in infectious mononucleosis].

作者信息

Tamarova L D, Filatov F P, Gasparian M O, Barinskiĭ I F

出版信息

Vopr Virusol. 1976 Mar-Apr(2):191-5.

PMID:779272
Abstract

This is the first study in this country of sera from patients with infectious mononucleosis and other infectious diseases (control group) for determination of complement-fixing antibody to the soluble (S) antigen and of fluorescent antibody to the virus capsid antigen (VCA) of Epstein-Barr virus. It was established that the CFT and the immunofluorescence test could be used for diagnosis of infectious mononucleosis only on a limited scale because of the lack of complement-fixing antibody in patients early in the convalescent period and because of the presence of complement-fixing and fluorescent antibody in a high per cent of patients of the control group.

摘要

这是该国首次针对传染性单核细胞增多症患者及其他传染病患者(对照组)的血清开展的研究,旨在测定针对爱泼斯坦-巴尔病毒可溶性(S)抗原的补体结合抗体以及针对病毒衣壳抗原(VCA)的荧光抗体。研究发现,补体结合试验(CFT)和免疫荧光试验仅能在有限范围内用于传染性单核细胞增多症的诊断,原因在于恢复期早期患者缺乏补体结合抗体,且对照组中相当比例的患者存在补体结合抗体和荧光抗体。

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