Stepina V N, Gurtsevich V E, Petukhova V I, Mazurenko N P
Vopr Virusol. 1976 Mar-Apr(2):196-9.
A high level of humoral antibody to the capsid antigen of Epstein-Barr virus was found in sera from patients with infectious mononucleosis. For detection of antibody, the method of indirect immunofluorescence in fixed P3HEHR cells of Burkitt's lymphoma was used. Sera from normal subjects were also shown to contain antibody to the capsid antigen of Epstein-Barr virus, but the titers were 5--10 times lower than in the sera from infectious mononucleosis patients. The occurrance of high titers of antibody to EBV in the sera from patients with infectious mononucleosis is diagnostic for IM and may be used for practical purposes.
在传染性单核细胞增多症患者的血清中发现了针对EB病毒衣壳抗原的高水平体液抗体。为检测抗体，采用了在伯基特淋巴瘤的固定P3HEHR细胞中进行间接免疫荧光的方法。正常受试者的血清也显示含有针对EB病毒衣壳抗原的抗体，但滴度比传染性单核细胞增多症患者血清中的低5至10倍。传染性单核细胞增多症患者血清中高滴度的EBV抗体的出现对IM具有诊断意义，可用于实际目的。
