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脑电图在窒息新生儿中的预后价值。

The prognostic value of the EEG in asphyxiated newborns.

作者信息

van Lieshout H B, Jacobs J W, Rotteveel J J, Geven W, v't Hof M

机构信息

Department of Clinical Neurophysiology, Academic Hospital Nijmegen, The Netherlands.

出版信息

Acta Neurol Scand. 1995 Mar;91(3):203-7. doi: 10.1111/j.1600-0404.1995.tb00435.x.

Abstract

Peripartal asphyxia is still one of the most important factors of neonatal morbidity and mortality and accounts for the majority of non-progressive neurological deficits seen in children. A set of evaluations that may consistently predict outcome in this patient population would be valuable. The purpose of the present retrospective study was to investigate the prognostic value of the early neonatal EEG and Sarnat scoring obtained in 23 asphyxiated term newborns. All infants met strict entrance criteria, regarding asphyxia, and received standard treatment. The relationship between the Sarnat scoring, the early EEG findings, and the clinical follow up examination (at 1,5-7 years) were studied using the Pearson Correlation test and multiple regression. Our study clearly demonstrates a strong correlation between the early neonatal EEG and outcome, even regarding the prediction of minor sequelae (r = 0.79, p < 0.0001). The early neonatal EEG is more accurate in predicting the ultimate clinical outcome than the Sarnat scoring.

摘要

围产期窒息仍然是新生儿发病和死亡的最重要因素之一,并且是儿童中所见大多数非进行性神经功能缺损的原因。一组能够始终如一地预测该患者群体预后的评估方法将很有价值。本项回顾性研究的目的是调查23例足月窒息新生儿的早期新生儿脑电图(EEG)和萨纳特评分的预后价值。所有婴儿均符合关于窒息的严格入选标准,并接受了标准治疗。使用Pearson相关检验和多元回归研究了萨纳特评分、早期脑电图结果与临床随访检查(1.5 - 7岁)之间的关系。我们的研究清楚地表明,早期新生儿脑电图与预后之间存在很强的相关性,即使对于轻微后遗症的预测也是如此(r = 0.79,p < 0.0001)。早期新生儿脑电图在预测最终临床结果方面比萨纳特评分更准确。

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