Saitoh H, Nomura A, Osaka M, Sasabe N, Atarashi H, Hayakawa H
First Department of Internal Medicine, Nippon Medical School, Tokyo, Japan.
Am J Cardiol. 1995 Jul 1;76(1):89-91. doi: 10.1016/s0002-9149(99)80811-x.
The important role of alpha 1-adrenoceptors in reperfusion ventricular arrhythmia is mentioned in the introduction. However, the present report is concerned with the sinus node. It is speculated that the decreased positive chronotropic action of alpha 1-adrenergic stimulation due to aging may contribute to the development of sick sinus syndrome.
引言中提到了α1肾上腺素能受体在再灌注性室性心律失常中的重要作用。然而,本报告关注的是窦房结。据推测,由于衰老导致α1肾上腺素能刺激的正性变时作用减弱可能促使病态窦房结综合征的发生。