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α1 - 肾上腺素能对人窦房结变时作用的发育变化

Developmental changes of alpha 1-adrenergic chronotropic action on human sinus node.

作者信息

Saitoh H, Nomura A, Osaka M, Sasabe N, Atarashi H, Hayakawa H

机构信息

First Department of Internal Medicine, Nippon Medical School, Tokyo, Japan.

出版信息

Am J Cardiol. 1995 Jul 1;76(1):89-91. doi: 10.1016/s0002-9149(99)80811-x.

DOI:10.1016/s0002-9149(99)80811-x
PMID:7793415
Abstract

The important role of alpha 1-adrenoceptors in reperfusion ventricular arrhythmia is mentioned in the introduction. However, the present report is concerned with the sinus node. It is speculated that the decreased positive chronotropic action of alpha 1-adrenergic stimulation due to aging may contribute to the development of sick sinus syndrome.

摘要

引言中提到了α1肾上腺素能受体在再灌注性室性心律失常中的重要作用。然而,本报告关注的是窦房结。据推测,由于衰老导致α1肾上腺素能刺激的正性变时作用减弱可能促使病态窦房结综合征的发生。

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Developmental changes of alpha 1-adrenergic chronotropic action on human sinus node.α1 - 肾上腺素能对人窦房结变时作用的发育变化
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Neurohumoral Control of Sinoatrial Node Activity and Heart Rate: Insight From Experimental Models and Findings From Humans.窦房结活动和心率的神经体液控制:来自实验模型的见解和人类研究结果
Front Physiol. 2020 Mar 3;11:170. doi: 10.3389/fphys.2020.00170. eCollection 2020.
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The effect of aging on phenylephrine response in normal subjects.衰老对正常受试者去氧肾上腺素反应的影响。
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Beta-adrenergic or parasympathetic inhibition, heart rate and cardiac output during normoxic and acute hypoxic exercise in humans.人体在常氧和急性低氧运动期间的β-肾上腺素能或副交感神经抑制、心率及心输出量
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