Armstrong P, Young C, McKeown D
Department of Anaesthesia, Royal Infirmary of Edinburgh, Scotland.
Can J Anaesth. 1990 Sep;37(6):656-8. doi: 10.1007/BF03006485.
One hundred and twenty unpremedicated patients undergoing gynaecological surgery were randomly allocated to one of three equal treatment groups to assess the effectiveness of ethyl chloride in producing instant skin anaesthesia to prevent the pain of venepuncture from a 20 G cannula. They received either no anaesthetic, 0.2 ml one per cent lidocaine plain intradermally or a ten-second spray of ethyl chloride at the cannulation site. Ethyl chloride produced skin anaesthesia that significantly reduced the pain of venepuncture. However, it was not as effective as intradermal lidocaine. It had no effect on vein visualisation or ease of cannulation. Ethyl chloride can be recommended as a method of producing instant skin anaesthesia.
120例未接受术前用药的妇科手术患者被随机分为三个同等治疗组，以评估氯乙烷产生即时皮肤麻醉以预防20G套管针静脉穿刺疼痛的有效性。他们分别接受无麻醉、0.2ml 1%的单纯利多卡因皮内注射或在穿刺部位喷十秒氯乙烷。氯乙烷产生的皮肤麻醉显著减轻了静脉穿刺的疼痛。然而，其效果不如皮内注射利多卡因。它对静脉可视化或穿刺难易程度没有影响。氯乙烷可作为一种产生即时皮肤麻醉的方法被推荐。
