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与对照患者相比,硅胶乳房植入物患者的血液硅水平是否升高?

Do patients with silicone-gel breast implants have elevated levels of blood silicon compared with control patients?

作者信息

Peters W, Smith D, Lugowski S, McHugh A, Baines C

机构信息

Division of Plastic Surgery, Wellesley Hospital, University of Toronto, Ontario, Canada.

出版信息

Ann Plast Surg. 1995 Apr;34(4):343-7. doi: 10.1097/00000637-199504000-00001.

Abstract

Whole blood silicon levels in 30 patients with silicon-gel implants (inserted between 1973 and 1991) were compared with those of 24 healthy, age-matched, female patients without breast implants using atomic absorption spectrometry with a graphite furnace. The blood silicon levels in the implant patients were significantly higher than those of controls (medians 33.45 vs 17.05 ng/ml; p = 0.005). Of the 30 patients with implants, 15 had received their implants between 1973 and 1985, and 15 had received implants between 1986 and 1991. Implants made between 1973 and 1985 have been shown to be weaker and to have higher silicone "bleed" levels than those made from 1986 onward. However, there were no significant differences in the blood silicone levels between these two groups of patients.

摘要

采用石墨炉原子吸收光谱法,对30例植入硅胶假体(于1973年至1991年间植入)的患者的全血硅水平,与24例未植入乳房假体、年龄匹配的健康女性患者的全血硅水平进行了比较。植入假体患者的血硅水平显著高于对照组(中位数分别为33.45 ng/ml和17.05 ng/ml;p = 0.005)。在30例植入假体的患者中,15例于1973年至1985年间植入假体,15例于1986年至1991年间植入假体。已证实,1973年至1985年间生产的假体比1986年以后生产的假体更易损坏,且硅酮“渗漏”水平更高。然而,这两组患者的血硅酮水平并无显著差异。

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