Macones G A, Johnson A, Tilley D, Wade R, Wapner R
Department of Obstetrics and Gynecology, Jefferson Medical College, Philadelphia, Pa., USA.
Fetal Diagn Ther. 1995 Mar-Apr;10(2):131-3. doi: 10.1159/000264219.
The in utero diagnosis of fetal myeloproliferative disease was made by cordocentesis following the ultrasound appearance of fetal hepatosplenomegaly and mild hydrops. The 2 fetuses reported both had leukocyte counts greater than 75,000/mm3 with a predominance of blast forms. In both cases the karyotype revealed trisomy 21.
