硅沉着病大鼠肝部分切除术后肝细胞增殖情况
Hepatocyte proliferation in silicotic rat liver after partial hepatectomy.
作者信息
Kanta J
机构信息
Department of Physiology, Faculty of Medicine, Charles University, Hradec Králové, Czech Republic.
出版信息
Physiol Res. 1994;43(6):383-5.
PMID:7794886
Abstract
Liver silicosis was induced in rats by an intravenous injection of silica particles. The presence of silicotic granulomas in the liver lowered the initial response of hepatocytes to partial (37%) hepatectomy and slowed down the decline in the number of dividing cells 6 days after the stimulus, but did not affect significantly the total number of mitotic cells.
摘要
通过静脉注射二氧化硅颗粒在大鼠中诱发肝矽肺。肝脏中矽肺肉芽肿的存在降低了肝细胞对部分（37%）肝切除的初始反应，并减缓了刺激后6天分裂细胞数量的下降，但对有丝分裂细胞的总数没有显著影响。
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