Vandevelde A G, Jenkins S G, Hardy P R
Division of Infectious Diseases, Baptist Medical Center, Jacksonville, Florida, USA.
Clin Infect Dis. 1995 Apr;20(4):1037-9. doi: 10.1093/clinids/20.4.1037.
We present the case of a young man with chronic Actinomyces naeslundii infection in the lower leg who underwent a below-the-knee amputation after unsuccessful attempts at diagnosing and eradicating the infection. Actinomycetic organisms from environmental sources can engender a dense fibrotic tissue response without fistulae. Such a response led to a painful, sclerosing, nonsuppurative infection of the bone and surrounding tissues in our patient. This clinical picture, at least the bony and periosteal reaction, was compatible with Garrè's osteomyelitis.
我们报告了一例患有小腿慢性内氏放线菌感染的年轻男性病例，在诊断和根除感染的尝试失败后，他接受了膝下截肢手术。来自环境源的放线菌生物体可引发致密的纤维化组织反应而不形成瘘管。这种反应导致了我们患者的骨骼和周围组织出现疼痛性、硬化性、非化脓性感染。这种临床表现，至少是骨和骨膜反应，与加雷氏骨髓炎相符。
