Rantala H, Uhari M, Hietala J
Department of Paediatrics, University of Oulu, Finland.
Acta Paediatr. 1995 Apr;84(4):407-10. doi: 10.1111/j.1651-2227.1995.tb13660.x.
The symptomatology of infections as well as immunological and virological findings were analysed using a logistic model in a survey of 58 children experiencing their first febrile seizures. These were then compared with findings in 116 age- and sex-matched controls with infections but no seizures. There were no statistically significant differences in the aetiology of infections between patients and controls. High temperature was the only variable to explain the occurrence of febrile seizures in the logistic model after adjusting for duration of symptoms (partial correlation coefficient in logistic model, r = 0.31). The duration of symptoms before hospitalization was shorter in patients than in controls (mean 1.0 and 3.6 days). With a longer duration of symptoms, the likelihood of seizures diminished (r = -0.34). Patients in the seizure group had a significantly higher temperature at home than controls before hospitalization (39.4 versus 38.8 degrees C). Our findings of higher temperatures in children with febrile seizures supports its importance as the most important triggering factor in febrile convulsions.
在一项针对58名首次发生热性惊厥儿童的调查中，运用逻辑模型分析了感染的症状学以及免疫学和病毒学检查结果。然后将这些结果与116名年龄和性别匹配、患有感染但未发生惊厥的对照儿童的检查结果进行比较。患者与对照儿童在感染病因方面无统计学显著差异。在对症状持续时间进行校正后，高温是逻辑模型中唯一能解释热性惊厥发生的变量（逻辑模型中的偏相关系数，r = 0.31）。患者住院前症状持续时间比对照儿童短（平均1.0天和3.6天）。症状持续时间越长，惊厥发生的可能性越小（r = -0.34）。惊厥组患者住院前在家时的体温显著高于对照儿童（39.4摄氏度对38.8摄氏度）。我们关于热性惊厥儿童体温较高的研究结果支持了高温作为热性惊厥最重要触发因素的重要性。
