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青少年酒精和药物滥用者的戒断及依赖症状。

Withdrawal and dependency symptoms among adolescent alcohol and drug abusers.

作者信息

Stewart D G, Brown S A

机构信息

San Diego State University/University of California, San Diego Joint Doctoral Program in Clinical Psychology, USA.

出版信息

Addiction. 1995 May;90(5):627-35. doi: 10.1046/j.1360-0443.1995.9056274.x.

Abstract

Due to differences in duration, intensity and topography of alcohol and drug use patterns, the withdrawal and dependency symptoms of adolescent substance abusers may differ from those of adult substance abusers. To explore these potential differences, 166 adolescents recruited from inpatient alcohol and drug treatment programs in the USA were assessed for alcohol and other drug withdrawal and dependency symptoms. Teens were administered the Customary Drinking and Drug Use Record following 2 weeks of abstinence and evaluated for recent (< 3 months) DSM-III-R psychoactive substance withdrawal and dependency symptoms. Adolescents were all multiple substance users with a life-time average of 4.27 drugs used in addition to alcohol. Amphetamines were the most frequently used drug (50% of sample) and the most prevalent withdrawal symptoms were those associated with central stimulant use. However, the number of different withdrawal symptoms (M = 11.27) was greater than expected for uncomplicated stimulant withdrawal or withdrawal from any single substance. On average, participants reported dependency symptoms more than DSM-III-R criteria for the diagnosis of alcohol dependency (M = 3.30), as well as dependency on their two most frequently used drugs. Heavy alcohol and cigarette use were found to exacerbate withdrawal symptoms of other drugs. These findings highlight the importance of assessing adolescent substance abusers for withdrawal from and dependency on multiple substances.

摘要

由于酒精和药物使用模式在持续时间、强度和特征方面存在差异,青少年药物滥用者的戒断症状和依赖症状可能与成人药物滥用者不同。为了探究这些潜在差异,对从美国住院酒精和药物治疗项目招募的166名青少年进行了酒精及其他药物戒断和依赖症状评估。在青少年禁欲两周后,让他们填写《习惯饮酒和药物使用记录》,并评估其近期(<3个月)DSM-III-R精神活性物质戒断和依赖症状。青少年均为多种药物使用者,除酒精外,一生平均使用4.27种药物。苯丙胺是最常使用的药物(占样本的50%),最常见的戒断症状是与使用中枢兴奋剂相关的症状。然而,不同戒断症状的数量(M = 11.27)比单纯兴奋剂戒断或任何单一物质戒断预期的要多。平均而言,参与者报告的依赖症状超过了DSM-III-R中酒精依赖诊断标准(M = 3.30),以及对其最常使用的两种药物的依赖。发现大量饮酒和吸烟会加剧其他药物的戒断症状。这些发现凸显了评估青少年药物滥用者多种物质戒断和依赖情况的重要性。

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