Elefteriades J A, Kron I L
Yale University School of Medicine, New Haven, Connecticut, USA.
Cardiol Clin. 1995 Feb;13(1):35-42.
Concurrent, independent clinical series at Yale University and the University of Virginia demonstrate an important role for CABG in patients with advanced ischemic cardiomyopathy. It is found that CABG can be performed safely in these patients, both angina and congestive heart failure states improve, ejection fraction increases substantially, and good long-term longevity is achieved. Despite prior concerns, the internal mammary conduit can be used safely in these patients. It appears that CABG serves to protect viable noninfarcted muscle and to recruit hibernating ischemic muscle. CABG is suggested as an alternative to heart transplantation in this patient group.
耶鲁大学和弗吉尼亚大学同时开展的独立临床系列研究表明,冠状动脉旁路移植术(CABG)在晚期缺血性心肌病患者中发挥着重要作用。研究发现,在这些患者中进行CABG手术是安全的,心绞痛和充血性心力衰竭状态均得到改善,射血分数大幅增加,并实现了良好的长期生存率。尽管此前存在担忧,但胸廓内动脉移植血管在这些患者中可以安全使用。似乎CABG有助于保护存活的非梗死心肌并促使冬眠的缺血心肌恢复活力。对于这一患者群体,建议将CABG作为心脏移植的替代方案。