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郊区诊所中铅中毒的患病率。

Prevalence of lead poisoning in a suburban practice.

作者信息

Striph K B

机构信息

Family Physicians Association, Flower Hospital, Sylvania, Ohio, USA.

出版信息

J Fam Pract. 1995 Jul;41(1):65-71.

PMID:7798067
Abstract

BACKGROUND

The purpose of this study was to determine the prevalence of elevated blood lead levels (EBLLS, lead > or = 10 micrograms/dL [0.48 mumol/L]) in a suburban family practice setting and to assess the utility of a questionnaire as an alternative to universal screening in identifying individuals with EBLL in a low-risk population.

METHODS

Parents bringing children aged 1 through 3 years into the office for any type of visit were offered the opportunity to complete a questionnaire concerning risk for lead poisoning and to obtain free blood lead testing for their child. No child in this study had previously been tested for lead toxicity. The lead levels found on testing were correlated with the questionnaire results.

RESULTS

Two hundred thirty-two children with an average age of 20 months were tested. Blood lead levels ranged from 0 to 53 micrograms/dL (2.56 mumol/L). Elevated blood lead levels were found in 5.6% of the study population. The five questions suggested by the Centers for Disease Control and Prevention (CDC) were taken as a group, and any "yes" or "don't know" response was considered a risk factor. These questions had a sensitivity of 84.6% and a specificity of 41.6% in identifying children with EBLL. An additional question regarding residence in a home built before 1960 (or not knowing the age of the home) was a better screening test for EBLL (sensitivity 92.3%, specificity 57.1%) than the five CDC questions. Lower household income was associated with an EBLL, but sex, race, and home location (urban, suburban, rural) were not.

CONCLUSIONS

Risk-assessment questionnaires are useful tools in selecting children who are at risk for an EBLL from low-risk populations. Comparison of this study with similar studies suggests that the most useful questions for this purpose may vary according to location. In this and other studies to date, however, questionnaires show less than 100% sensitivity in identifying children with EBLL.

摘要

背景

本研究的目的是确定在郊区家庭医疗环境中血铅水平升高(EBLLS,铅≥10微克/分升[0.48微摩尔/升])的患病率,并评估问卷作为低风险人群中识别血铅水平升高个体的通用筛查替代方法的效用。

方法

带1至3岁儿童因任何类型就诊前来诊所的家长有机会填写一份关于铅中毒风险的问卷,并为其孩子获得免费血铅检测。本研究中没有儿童之前接受过铅毒性检测。检测发现的铅水平与问卷结果相关。

结果

对平均年龄为20个月的232名儿童进行了检测。血铅水平范围为0至53微克/分升(2.56微摩尔/升)。在研究人群中发现5.6%的血铅水平升高。疾病控制和预防中心(CDC)提出的五个问题作为一组,任何“是”或“不知道”的回答都被视为风险因素。这些问题在识别血铅水平升高儿童方面的敏感性为84.6%,特异性为41.6%。关于居住在1960年以前建造的房屋中(或不知道房屋年龄)的另一个问题是比CDC的五个问题更好的血铅水平升高筛查测试(敏感性92.3%,特异性57.1%)。较低的家庭收入与血铅水平升高有关,但性别、种族和家庭位置(城市、郊区、农村)无关。

结论

风险评估问卷是从低风险人群中选择有血铅水平升高风险儿童的有用工具。本研究与类似研究的比较表明,为此目的最有用的问题可能因地点而异。然而,在本研究和迄今为止的其他研究中,问卷在识别血铅水平升高儿童方面的敏感性低于100%。

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