Haan M N, Gerson M, Zishka B A
University of California, School of Medicine, Department of Community Health, Davis 95616, USA.
Pediatrics. 1996 Jan;97(1):79-83.
To estimate the prevalence of elevated blood lead levels in children receiving well-care checkups; and to evaluate the effectiveness of certain key risk factors in detecting children at higher risk for elevated blood lead levels.
Cross-sectional study.
Two facilities of the Kaiser Permanente Medical Care Program (KPMCP) health maintenance organization (HMO), northern California region.
Six hundred thirty-six children, aged 12 to 60 months, who were seen at four KPMCP facilities in two subregions for a well-care checkup from September 1991 through August 1992.
Blood samples were collected from each child and analyzed for lead content. Participating parents completed a questionnaire that included questions recommended by the Centers for Disease Control and Prevention (CDC) about the child's and the parents' lead exposure via home, workplace, and hobbies.
Ninety-six percent of the children had blood lead levels under 10 micrograms/dL. Blood lead levels declined with increasing age and were higher for black children compared with whites. Age of residential housing, mother's education, and residence in an old house with peeling paint had low sensitivity and positive predictive value for identifying children with blood lead levels over 10 micrograms/dL.
Universal routine screening for elevated blood lead levels in children in an employed, HMO-insured population is not warranted on grounds of prevalence. Responses to CDC questions do not effectively identify high-risk children in this population.
评估接受健康体检儿童血铅水平升高的患病率;并评估某些关键风险因素在检测血铅水平升高风险较高儿童方面的有效性。
横断面研究。
加利福尼亚州北部地区凯撒永久医疗保健计划(KPMCP)健康维护组织(HMO)的两家机构。
1991年9月至1992年8月期间在两个分区的四个KPMCP机构接受健康体检的636名12至60个月大的儿童。
采集每个儿童的血样并分析铅含量。参与研究的家长完成一份问卷,其中包括疾病控制与预防中心(CDC)推荐的关于儿童及其家长通过家庭、工作场所和爱好接触铅的问题。
96%的儿童血铅水平低于10微克/分升。血铅水平随年龄增长而下降,黑人儿童的血铅水平高于白人儿童。居住房屋的年龄、母亲的教育程度以及居住在油漆剥落的老房子里,对于识别血铅水平超过10微克/分升的儿童,敏感性和阳性预测值较低。
基于患病率,对于就业的、由HMO承保人群中的儿童进行普遍常规血铅水平升高筛查并无必要。对CDC问题的回答并不能有效识别该人群中的高危儿童。