Panich A, Charnvej L
Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University, Thailand.
J Med Assoc Thai. 1993 Dec;76(12):672-6.
A cross-over, single blind trial of MST and MSS in relieving pain of advanced cancer patients is described. Forty-nine cases completed the study. Both MST and MSS gave equally excellent pain relief in the patients as judged by the pain score of VAS and pain rating scale by a nurse, and the duration of sleep. The daily effective dose was 55.5 +/- 19.7 mg for MST and 61.0 +/- 11.0 mg of MSS.
本文描述了一项关于美施康定(MST)和硫酸吗啡控释片(MSS)缓解晚期癌症患者疼痛的交叉单盲试验。49例患者完成了该研究。根据视觉模拟评分法(VAS)的疼痛评分、护士的疼痛评级量表以及睡眠时间判断,MST和MSS在患者中均能提供同样出色的疼痛缓解效果。MST的每日有效剂量为55.5±19.7毫克,MSS为61.0±11.0毫克。