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正电子发射断层扫描(PET)与单光子发射计算机断层扫描(SPECT)在鉴别脑放射性坏死与肿瘤复发中的应用

PET versus SPECT in distinguishing radiation necrosis from tumor recurrence in the brain.

作者信息

Buchpiguel C A, Alavi J B, Alavi A, Kenyon L C

机构信息

Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia 19104.

出版信息

J Nucl Med. 1995 Jan;36(1):159-64.

PMID:7799071
Abstract

Two cases of postsurgical brain tumor evaluation in which MRI was inconclusive are discussed. Functional imaging techniques, such as FDG-PET and 201TI SPECT, were used in both cases for distinguishing radiation necrosis from tumor recurrence. These methods proved to be complimentary. For Patient 1, FDG-PET showed more limitations compared to 201TI SPECT. FDG-PET results on the other hand, were consistent with the final diagnosis and the SPECT image was false positive for tumor recurrence in Patient 2.

摘要

本文讨论了两例术后脑肿瘤评估病例,其中MRI检查结果不明确。在这两例病例中均使用了功能成像技术,如FDG-PET和201TI SPECT,以区分放射性坏死与肿瘤复发。这些方法被证明是互补的。对于患者1,与201TI SPECT相比,FDG-PET显示出更多局限性。另一方面,FDG-PET结果与最终诊断一致,而患者2的SPECT图像在肿瘤复发方面出现假阳性。

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