Billiard M, Dolenc L, Aldaz C, Ondze B, Besset A
Service de Neurologie B. Hospital Gui de Chauliac, Montpellier, France.
J Psychosom Res. 1994;38 Suppl 1:41-7. doi: 10.1016/0022-3999(94)90134-1.
Thirty-six subjects affected with hypersomnia associated with mood disorders, 31 with a diagnosis of dysthymia, 4 with a diagnosis of bipolar disorder and one with a diagnosis of major recurrent depression underwent standardized polysomnographic procedures including night 1, MSLT and night 2 (uninterrupted). 36.1% of these subjects had a reduced or intermediate mean sleep latency on the MSLT and 13.8% slept over 9 hr at night. In addition 17 of these subjects underwent prolonged polysomnography during day 2. In comparison with eight subjects affected with idiopathic hypersomnia, mean sleep latency on the MSLT was significantly longer and total sleep time during night 2 and during night 2 plus day 2 was significantly lower in subjects affected with hypersomnia associated with mood disorders. It is concluded that a positive diagnosis of hypersomnia associated with a mood disorder requires both behavioral observation and polysomnography. Among these subjects there may be subjects with well-documented hypersomnia and subjects with anergia facilitating or mimicking sleep.
36名患有与情绪障碍相关的发作性睡病的受试者，31名被诊断为心境恶劣，4名被诊断为双相情感障碍，1名被诊断为复发性重度抑郁症，他们接受了标准化的多导睡眠图检查程序，包括第1晚、多次睡眠潜伏期试验（MSLT）和第2晚（不间断）。这些受试者中36.1%在MSLT上的平均睡眠潜伏期缩短或处于中等水平，13.8%夜间睡眠超过9小时。此外，其中17名受试者在第2天进行了延长的多导睡眠图检查。与8名患有特发性发作性睡病的受试者相比，患有与情绪障碍相关的发作性睡病的受试者在MSLT上的平均睡眠潜伏期显著更长，在第2晚以及第2晚加第2天期间的总睡眠时间显著更低。结论是，对与情绪障碍相关的发作性睡病的阳性诊断需要行为观察和多导睡眠图检查。在这些受试者中，可能有记录良好的发作性睡病患者，以及存在无力状态促进或模拟睡眠的患者。
