评估直接观察治疗（DC-ART）时的其他特殊考虑因素：患者分层的必要性。
Other special considerations in assessing DC-ART: The need for patient stratification.
作者信息
Edmonds J, Bosi Ferraz M
机构信息
Department of Rheumatology, St. George Hospital, University of New South Wales, Sydney, Australia.
出版信息
J Rheumatol Suppl. 1994 Sep;41:50-1.
PMID:7799385
Abstract
Given the heterogeneity of rheumatoid arthritis (RA), even in disease of the same duration, it seems likely that some therapeutic regimens will satisfy DC-ART criteria to different degrees in different strata of patients with RA. Since it entails its own problems, it is recommended that the value and feasibility of stratification be evaluated before any attempt to design a DC-ART trial.
摘要
鉴于类风湿性关节炎（RA）的异质性，即使在病程相同的疾病中，某些治疗方案在不同分层的RA患者中似乎也可能在不同程度上满足基于疾病控制的抗风湿治疗（DC-ART）标准。由于分层本身存在问题，建议在尝试设计DC-ART试验之前评估分层的价值和可行性。
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