Viney M E
Division of Biological Sciences, University of Edinburgh, UK.
Parasitology. 1994 Nov;109 ( Pt 4):511-5. doi: 10.1017/s0031182000080768.
Strongyloides ratti has a complex life-cycle with two adult generations, one free-living and dioecious and one parasitic and female only. The parasitic females reproduce by parthenogenesis, but it is unclear whether this is mitotic or meiotic in nature. This question has been addressed genetically by analysing the progeny of parasitic females that were heterozygous at an actin locus for evidence of allelic segregation. Such progeny were similarly heterozygous showing that segregation had not occurred. It was therefore concluded that reproduction in the parasitic female of S. ratti is functionally mitotic.
鼠类圆线虫具有复杂的生命周期，有两代成虫，一代为自由生活且雌雄异体，另一代为寄生且仅为雌性。寄生雌性通过孤雌生殖进行繁殖，但尚不清楚其本质上是有丝分裂还是减数分裂。通过分析在肌动蛋白基因座处杂合的寄生雌性的后代以寻找等位基因分离的证据，从遗传学角度解决了这个问题。这些后代同样是杂合的，表明没有发生分离。因此得出结论，鼠类圆线虫寄生雌性的繁殖在功能上是有丝分裂。
