Abel E L
C.S. Mott Center for Human Growth and Development, Department of Obstetrics and Gynecology, Detroit, MI 48201.
Physiol Behav. 1994 Oct;56(4):677-81. doi: 10.1016/0031-9384(94)90226-7.
Two experiments were conducted to examine physiological variables associated with the immobility response in the forced swim test. The first study compared the effects of water immersion, treadmill running, and foot shock, and showed that the time-related pattern of reactions to these three conditions, especially those involving lactate, glucose, anion gap (a measure of metabolic acidosis), and carbon dioxide differed significantly. The second study examined the role of food deprivation, and showed that this manipulation does not affect the behavior or physiological response of rats to testing. These results indicate that the physiological changes occurring during the forced swim are not simply due to increased physical activity or stress.
进行了两项实验，以检验与强迫游泳试验中的不动反应相关的生理变量。第一项研究比较了水浸、跑步机跑步和足部电击的影响，结果表明，对这三种情况的时间相关反应模式，尤其是涉及乳酸、葡萄糖、阴离子间隙（代谢性酸中毒的一种衡量指标）和二氧化碳的反应模式，存在显著差异。第二项研究考察了食物剥夺的作用，结果表明这种操作不会影响大鼠在测试中的行为或生理反应。这些结果表明，强迫游泳过程中发生的生理变化并非仅仅由于身体活动增加或应激所致。
