Rizk S N, Assimacopoulos C A, Ryan J J
Department of Surgery, USD School of Medicine, Sioux Falls.
S D J Med. 1994 Oct;47(10):343-6.
Carcinoma of the breast occurs so infrequently in men that it is not at al well known either to patients or physicians. The causes of breast cancer in men are unknown. The most common clinical manifestation of breast cancer in men is a painless, firm subareolar mass or a mass in the upper outer quadrant of the breast. Diagnosis can be confirmed by fine-needle aspiration or surgical biopsy. Infiltrating ductal carcinoma is the predominant histologic type. After primary surgical treatment, men with axillary lymph node metastasis should receive adjuvant systemic chemotherapy. The use of radiation therapy for local control of the disease is recommended if there is invasion of the chest wall. Because most men with carcinoma of the breast have estrogen and progesterone-receptor positive tumors, breast cancer in men is likely to respond to hormonal manipulation.
男性乳腺癌极为罕见，以至于患者和医生对此都知之甚少。男性乳腺癌的病因尚不明确。男性乳腺癌最常见的临床表现是乳晕下无痛性、质地坚硬的肿块或乳房外上象限的肿块。细针穿刺抽吸或手术活检可确诊。浸润性导管癌是主要的组织学类型。在进行初次手术治疗后，有腋窝淋巴结转移的男性应接受辅助性全身化疗。如果胸壁受到侵犯，建议使用放射治疗来局部控制疾病。由于大多数男性乳腺癌患者的肿瘤雌激素和孕激素受体呈阳性，男性乳腺癌可能对激素治疗有反应。
