Jackson C A, deLahunta A, Dykes N L, Divers T J
Department of Clinical Sciences, New York State College of Veterinary Medicine, Ithaca 14853.
Vet Rec. 1994 Sep 3;135(10):228-30. doi: 10.1136/vr.135.10.228.
Cholesterinic granulomas have been previously reported as an incidental post mortem in horses. Three adult horses with diencephalic dysfunction due to cholesterinic granulomas are described. All the horses exhibited profound depression, somnolence and reluctance to move. One horse experienced generalised seizures. Cerebrosinal fluid was xanthochromic with an elevated total protein in two of the cases evaluated. The large cholesterinic granulomas caused expansion of the lateral ventricle and secondary hydrocephalus due to the build up of cerebrospinal fluid behind the mass. Cholesterinic granulomas are believed to result from choroid plexus congestion and haemorrhage.
胆固醇性肉芽肿此前曾作为马匹死后的偶然发现被报道过。本文描述了三匹因胆固醇性肉芽肿导致间脑功能障碍的成年马。所有马匹均表现出深度抑郁、嗜睡和不愿活动。其中一匹马出现全身性癫痫发作。在评估的两例病例中，脑脊液呈黄变，总蛋白升高。巨大的胆固醇性肉芽肿导致侧脑室扩张，并因肿块后方脑脊液积聚而继发脑积水。据信，胆固醇性肉芽肿是由脉络丛充血和出血引起的。
