Jacobsen S J, Sargent D J, Atkinson E J, O'Fallon W M, Melton L J
Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905.
Am J Epidemiol. 1995 Jan 1;141(1):79-83. doi: 10.1093/oxfordjournals.aje.a117348.
Previous studies have demonstrated seasonal increases in hip fracture incidence, but none have directly assessed the influence of inclement weather on this seasonality. In this study, the daily occurrence of hip fracture among women aged 45 years and older in Rochester, Minnesota, from 1952 through 1989 was ascertained using the resources of the Rochester Epidemiology Project and compared with the occurrence of inclement weather as recorded in hourly readings by the National Weather Service in Rochester for the same time period. Among the women aged 45-74 years, the risk of hip fracture was increased on days with snow (relative risk (RR) = 1.41, 95% confidence interval (CI) 1.10-1.81) or freezing rain (RR = 1.82, 95% CI 1.27-2.62). In this group, the elevated risk of hip fracture in winter, compared with summer (RR = 1.44, 95% CI 1.0-2.09), was reduced after controlling for weather (RR = 1.16, 95% CI 0.81-1.65). Among women aged 75 years and older, ice and snow were not strongly related to fracture occurrence. The winter-related increase in risk (RR = 1.16, 95% CI 0.96-1.40) was essentially unchanged after controlling for weather and was similar to the weather-adjusted seasonality of hip fracture occurrence in younger women. These data suggest that there are factors other than weather that may be linked to the seasonal pattern in hip fracture occurrence and that operate at all ages.
以往研究已证实髋部骨折发病率存在季节性上升,但尚无研究直接评估恶劣天气对这种季节性的影响。在本研究中,利用罗切斯特流行病学项目的资源确定了1952年至1989年明尼苏达州罗切斯特市45岁及以上女性髋部骨折的每日发病情况,并与同一时期罗切斯特市国家气象局每小时记录的恶劣天气情况进行了比较。在45 - 74岁的女性中,下雪天(相对风险(RR)= 1.41,95%置信区间(CI)1.10 - 1.81)或冻雨天气(RR = 1.82,95% CI 1.27 - 2.62)时髋部骨折风险增加。在该组中,与夏季相比,冬季髋部骨折风险升高(RR = 1.44,95% CI 1.0 - 2.09),在控制天气因素后风险降低(RR = 1.16,95% CI 0.81 - 1.65)。在75岁及以上的女性中,冰雪与骨折发生没有强烈关联。控制天气因素后,与冬季相关的风险增加(RR = 1.16,95% CI 0.96 - 1.40)基本未变,且与年轻女性经天气调整后的髋部骨折发生季节性相似。这些数据表明,除天气因素外,可能还有其他因素与髋部骨折发生的季节性模式相关,且在所有年龄段都起作用。