Sanchez-Capuchino A, McConachie I
Department of Anaesthesia, Royal Oldham Hospital, Lancashire.
Anaesthesia. 1994 Oct;49(10):912-4. doi: 10.1111/j.1365-2044.1994.tb04275.x.
This study investigates the changes in serum magnesium levels after major gastrointestinal surgery and evaluates if Plasma-Lyte 148 used as maintenance fluid influences these changes in the peri-operative period. Thirty patients presenting for procedures ranging from anterior rectal resection to thoraco-abdominal cardio-oesophagectomy were randomly allocated into two groups, one of which received compound sodium lactate solution as the maintenance crystalloid during the intra- and postoperative period, and the other Plasma-Lyte 148, a magnesium-containing crystalloid solution. Serum magnesium levels were measured pre-operatively, in the immediate recovery period and 24 h postoperatively. The results showed a statistically significant (p < 0.05) reduction in the magnesium levels in both groups. The reduction was less marked in the Plasma-Lyte group but this did not achieve statistical significance (p > 0.05) compared with the compound sodium lactate group.
本研究调查了胃肠道大手术后血清镁水平的变化，并评估了作为维持液使用的平衡液148在围手术期是否会影响这些变化。30例接受从前直肠切除到胸腹段贲门食管切除术等手术的患者被随机分为两组，其中一组在术中和术后接受复方乳酸钠溶液作为维持晶体液，另一组接受平衡液148（一种含镁晶体溶液）。在术前、即刻恢复期和术后24小时测量血清镁水平。结果显示两组镁水平均有统计学意义的降低（p<0.05）。平衡液组的降低不太明显，但与复方乳酸钠组相比未达到统计学意义（p>0.05）。
