Simon H K, Steele D W
Department of Pediatrics, Brown University, Providence, Rhode Island.
Ann Emerg Med. 1995 Jan;25(1):111-4. doi: 10.1016/s0196-0644(95)70365-9.
Three children who presented with localized vesicular rash in the diaper area were found to have primary varicella-zoster infections. Primary varicella can closely mimic genital herpes simplex virus (HSV 1 or 2), which may be an indicator of sexual abuse. To avoid unfounded investigation for sexual abuse, primary varicella-zoster infection must be included in the differential diagnosis. Direct fluorescent antibody testing is a sensitive and specific diagnostic test that can be used to distinguish HSV 1 or 2 from varicella-zoster.
三名在尿布区域出现局部水疱疹的儿童被发现患有原发性水痘-带状疱疹感染。原发性水痘可能与单纯疱疹病毒（HSV 1或2）引起的生殖器疱疹极为相似，而后一种情况可能提示性虐待。为避免对性虐待进行无端调查，在鉴别诊断中必须考虑原发性水痘-带状疱疹感染。直接荧光抗体检测是一种灵敏且特异的诊断测试，可用于区分HSV 1或2与水痘-带状疱疹病毒。
