Heuck D, Dinger E, Voigt M, Claus H, Witte W
Robert Koch-Institut, Bereich Wernigerode des Bundesgesundheitsamtes.
Zentralbl Hyg Umweltmed. 1994 Aug;196(1):52-69.
Nosocomial infections over an 11 years period were monitored prospectively in a district hospital. A total of nosocomial infections among 162.197 patients discharged from 1980-1990 were analyzed. The incidence rate of nosocomial infections was 3.6%. The predominant isolates were Escherichia coli and Staphylococcus aureus (11%). The highest rates of S. aureus infections were established in wound infections and skin and mucosal infections at surgery, gynaecology and paediatrics departments. The number of multiply resistant S. aureus strains has decreased and those of sensitive isolates has increased. 72% of 652 S. aureus isolates have been typed by phage typing and biotyping. Statistical analysis could not establish a significant relationship between phage patterns and nosocomial infections. The spectrum of phage patterns of these nosocomial strains was the same as those of the endogenous colonization of men. Nosocomial outbreaks could not been realized.
在一家区级医院对11年间的医院感染进行了前瞻性监测。分析了1980年至1990年出院的162197例患者中的医院感染总数。医院感染发病率为3.6%。主要分离菌为大肠杆菌和金黄色葡萄球菌（11%）。金黄色葡萄球菌感染率最高的是外科、妇科和儿科的伤口感染以及皮肤和黏膜感染。多重耐药金黄色葡萄球菌菌株数量减少，敏感分离株数量增加。652株金黄色葡萄球菌分离株中有72%通过噬菌体分型和生物分型进行了分型。统计分析未能确定噬菌体模式与医院感染之间的显著关系。这些医院菌株的噬菌体模式谱与男性内源性定植的谱相同。未发现医院感染暴发情况。
