McFadzean R, Brosnahan D, Doyle D, Going J, Hadley D, Lee W
Department of Neuro-ophthalmology, Tennent Institute, University of Glasgow, Scotland.
J Neuroophthalmol. 1994 Sep;14(3):175-82. doi: 10.3109/01658109409024045.
A rare case of optic leptomeningeal carcinomatosis secondary to a rectal adenocarcinoma is recorded. The presentation of rectal disease with blindness is unique. A diagnostic quartet of symptoms and signs of leptomeningeal infiltration of the optic nerve sheath is proposed and its value emphasized by the inability of further investigation to confirm the clinical diagnosis. The investigation and treatment of leptomeningeal carcinomatosis is reviewed.
记录了一例罕见的继发于直肠腺癌的视神经软脑膜癌病。伴有失明症状的直肠疾病表现较为独特。提出了一组视神经鞘软脑膜浸润的诊断性症状和体征四重奏，并强调了进一步检查无法确诊临床诊断情况下该四重奏的价值。对软脑膜癌病的检查和治疗进行了综述。
