Czyz Craig, Blair Kyle, Bergstrom Reece
Division of Ophthalmology, Section Oculofacial Plastic and Reconstructive Surgery, Ohio University/OhioHealth Doctors Hospital, Columbus, Ohio, USA.
Case Rep Oncol. 2021 Feb 25;14(1):98-100. doi: 10.1159/000510808. eCollection 2021 Jan-Apr.
The most common presenting symptoms of leptomeningeal carcinomatosis (LC) are ocular manifestations with vision loss. There are multiple reports of undiagnosed LC causing sudden, complete, monocular vision loss as the presenting symptom; however, sudden bilateral vision loss 6 months following diagnosis has not been described. Any new ocular involvement or worsening of previous ocular symptoms warrants reimaging and prompt ophthalmology consultation, as this likely indicates disease progression. This report details a unique case of LC where a previously diagnosed patient developed sudden, complete, bilateral vision loss and multiple cranial nerve palsies with progression of LC on imaging.
柔脑膜癌病（LC）最常见的症状是眼部表现并伴有视力丧失。有多项关于未确诊的LC以突然、完全性单眼视力丧失为首发症状的报道；然而，尚未有关于诊断后6个月出现突然双侧视力丧失的描述。任何新的眼部受累情况或既往眼部症状的恶化都需要重新进行影像学检查并及时咨询眼科医生，因为这可能表明疾病进展。本报告详细介绍了一例独特的LC病例，一名先前已确诊的患者出现了突然、完全性双侧视力丧失以及多条颅神经麻痹，影像学检查显示LC病情进展。
