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皮肤癌概述。发病率与病因。

An overview of skin cancers. Incidence and causation.

作者信息

Marks R

机构信息

University of Melbourne, Department of Medicine, St. Vincent's Hospital, Fitzroy, Victoria, Australia.

出版信息

Cancer. 1995 Jan 15;75(2 Suppl):607-12. doi: 10.1002/1097-0142(19950115)75:2+<607::aid-cncr2820751402>3.0.co;2-8.

DOI:10.1002/1097-0142(19950115)75:2+<607::aid-cncr2820751402>3.0.co;2-8
PMID:7804986
Abstract

The incidence and mortality rates of skin cancer are rising in the United States and in many other countries. Concerns about stratospheric ozone depletion adding to the problem have made many organizations look at public and professional health programs as a possible solution. Early detection can reduce the problem in the short term, because mortality due to melanoma is clearly related to the depth of invasion of the tumor when it is removed. This is the factor which is amenable to change in an education program on early detection. Exposure to sunlight is clearly related to risk of development of skin cancer, including both melanoma and nonmelanoma skin cancers. This is the component of the equation of constitutional predisposition plus exposure to environmental risk factors leading to skin cancer that is amenable to change as a result of educational programs. On the basis of available data, there is a case for further development, provision, and evaluation of public and professional education programs designed to control what is becoming a major public health problem in the community.

摘要

在美国以及许多其他国家,皮肤癌的发病率和死亡率都在上升。由于担心平流层臭氧消耗会加剧这一问题,许多组织将公共和专业健康项目视为可能的解决方案。早期检测在短期内可以减轻问题,因为黑色素瘤导致的死亡率与肿瘤切除时的浸润深度明显相关。这是在早期检测教育项目中可以改变的因素。阳光照射显然与皮肤癌(包括黑色素瘤和非黑色素瘤皮肤癌)的发生风险相关。这是构成易患体质加上暴露于导致皮肤癌的环境风险因素这一方程式中的组成部分,而这一组成部分可通过教育项目加以改变。根据现有数据,有理由进一步开发、提供和评估旨在控制这一正成为社区主要公共卫生问题的公共和专业教育项目。

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